9 Essential Tips For Screwing Into MDF

9 Essential Tips For Screwing Into MDF. MDF can successfully be screwed together without it splitting by using a pilot hole before driving the screw in. Ordinary straight shanked wood screws can be used in MDF.. From my years of experience with the product, I have put together these 9 essential tips for screwing together MDF that will avoid splitting and result in strong joints every time.. Use a good quality MDF that has a good density.